Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression

E-cadherin inactivation underpins the progression of invasive lobular breast carcinoma (ILC). In ILC, p120-catenin (p120) translocates to the cytosol where it controls anchorage independence through the Rho-Rock signaling pathway, a key mechanism driving tumor growth and metastasis. We now demonstra...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: van de Ven, Robert A. H., Tenhagen, Milou, Meuleman, Wouter, van Riel, Jeske J. G., Schackmann, Ron C. J., Derksen, Patrick W. B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381336/
https://ncbi.nlm.nih.gov/pubmed/25713299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.018648
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