Down's-syndrome-related kinase Dyrk1A modulates the p120-catenin–Kaiso trajectory of the Wnt signaling pathway

The Wnt pathways contribute to many processes in cancer and development, with β-catenin being a key canonical component. p120-catenin, which is structurally similar to β-catenin, regulates the expression of certain Wnt target genes, relieving repression conferred by the POZ- and zinc-finger-domain-c...

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Autors principals: Hong, Ji Yeon, Park, Jae-Il, Lee, Moonsup, Muñoz, William A., Miller, Rachel K., Ji, Hong, Gu, Dongmin, Sokol, Sergei Y., McCrea, Pierre D.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2012
Matèries:
Short Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367828/
https://ncbi.nlm.nih.gov/pubmed/22389395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.086173
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