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Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members

Wnt signaling pathways have fundamental roles in animal development and tumor progression. Here, employing Xenopus embryos and mammalian cell lines, we report that the degradation machinery of the canonical Wnt pathway modulates p120-catenin protein stability through mechanisms shared with those reg...

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Detalhes bibliográficos
Main Authors: Hong, Ji Yeon, Park, Jae-il, Cho, Kyucheol, Gu, Dongmin, Ji, Hong, Artandi, Steven E., McCrea, Pierre D.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995616/
https://ncbi.nlm.nih.gov/pubmed/21098636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.067199
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