Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance

Metastatic breast cancer is the major cause of cancer-related death among women in the Western world. Invasive carcinoma cells are able to counteract apoptotic signals in the absence of anchorage, enabling cell survival during invasion and dissemination. Although loss of E-cadherin is a cardinal eve...

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Detalhes bibliográficos
Main Authors: Schackmann, Ron C.J., van Amersfoort, Miranda, Haarhuis, Judith H.I., Vlug, Eva J., Halim, Vincentius A., Roodhart, Jeanine M.L., Vermaat, Joost S., Voest, Emile E., van der Groep, Petra, van Diest, Paul J., Jonkers, Jos, Derksen, Patrick W.B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148719/
https://ncbi.nlm.nih.gov/pubmed/21747168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41695
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