αE‐catenin is a candidate tumor suppressor for the development of E‐cadherin‐expressing lobular‐type breast cancer

Although mutational inactivation of E‐cadherin (CDH1) is the main driver of invasive lobular breast cancer (ILC), approximately 10–15% of all ILCs retain membrane‐localized E‐cadherin despite the presence of an apparent non‐cohesive and invasive lobular growth pattern. Given that ILC is dependent on...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: de Groot, Jolien S, Ratze, Max AK, van Amersfoort, Miranda, Eisemann, Tanja, Vlug, Eva J, Niklaas, Mijanou T, Chin, Suet‐Feung, Caldas, Carlos, van Diest, Paul J, Jonkers, Jos, de Rooij, Johan, Derksen, Patrick WB
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2018
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055824/
https://ncbi.nlm.nih.gov/pubmed/29774524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5099
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