E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer

Despite the fact that loss of E-cadherin is causal to the development and progression of invasive lobular carcinoma (ILC), options to treat this major breast cancer subtype are limited if tumours develop resistance to anti-oestrogen treatment regimens. This study aimed to identify clinically targeta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Teo, Katy, Gómez-Cuadrado, Laura, Tenhagen, Milou, Byron, Adam, Rätze, Max, van Amersfoort, Miranda, Renes, Jojanneke, Strengman, Eric, Mandoli, Amit, Singh, Abhishek A., Martens, Joost H., Stunnenberg, Hendrik G., van Diest, Paul J., Brunton, Valerie G., Derksen, Patrick W. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193986/
https://ncbi.nlm.nih.gov/pubmed/30337563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33525-5
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