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Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice

Breast cancer is the most common malignancy in women of the Western world. Even though a large percentage of breast cancer patients show pathological complete remission after standard treatment regimes, approximately 30–40% are non-responsive and ultimately develop metastatic disease. To generate a...

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Bibliografiset tiedot
Päätekijät: Derksen, Patrick W. B., Braumuller, Tanya M., van der Burg, Eline, Hornsveld, Marten, Mesman, Elly, Wesseling, Jelle, Krimpenfort, Paul, Jonkers, Jos
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists Limited 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097456/
https://ncbi.nlm.nih.gov/pubmed/21282721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.006395
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