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An in vitro method for detecting genetic toxicity based on inhibition of RNA synthesis by DNA lesions

INTRODUCTION: A wide variety of DNA lesions such as ultraviolet light-induced photoproducts and chemically induced bulky adducts and crosslinks (intrastrand and interstrand) interfere with replication and lead to mutations and cell death. In the human body, these damages may cause cancer, inborn dis...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genes Environ
Päätekijät: Sonohara, Yuina, Iwai, Shigenori, Kuraoka, Isao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918014/
https://ncbi.nlm.nih.gov/pubmed/27350805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-015-0014-8
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