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Oligo swapping method for in vitro DNA repair substrate containing a single DNA lesion at a specific site

BACKGROUND: A wide variety of DNA lesions interfere with replication and transcription, leading to mutations and cell death. DNA repair mechanisms act upon these DNA lesions present in the genomic DNA. To investigate a DNA repair mechanism elaborately, an in vitro DNA repair substrate containing DNA...

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Détails bibliographiques
Publié dans:Genes Environ
Auteurs principaux: Yukutake, Mika, Hayashida, Mika, Shioi Aoki, Narumi, Kuraoka, Isao
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231255/
https://ncbi.nlm.nih.gov/pubmed/30459925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-018-0112-5
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