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An in vitro method for detecting genetic toxicity based on inhibition of RNA synthesis by DNA lesions
INTRODUCTION: A wide variety of DNA lesions such as ultraviolet light-induced photoproducts and chemically induced bulky adducts and crosslinks (intrastrand and interstrand) interfere with replication and lead to mutations and cell death. In the human body, these damages may cause cancer, inborn dis...
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| Publicado no: | Genes Environ |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918014/ https://ncbi.nlm.nih.gov/pubmed/27350805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-015-0014-8 |
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