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Fluorescence detection of cellular nucleotide excision repair of damaged DNA

To maintain genetic integrity, ultraviolet light-induced photoproducts in DNA must be removed by the nucleotide excision repair (NER) pathway, which is initiated by damage recognition and dual incisions of the lesion-containing strand. We intended to detect the dual-incision step of cellular NER, by...

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Detalhes bibliográficos
Main Authors: Toga, Tatsuya, Kuraoka, Isao, Watanabe, Shun, Nakano, Eiji, Takeuchi, Seiji, Nishigori, Chikako, Sugasawa, Kaoru, Iwai, Shigenori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081890/
https://ncbi.nlm.nih.gov/pubmed/24993089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05578
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