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Fluorescent probes for the analysis of DNA strand scission in base excision repair

We have developed fluorescent probes for the detection of strand scission in the excision repair of oxidatively damaged bases. They were hairpin-shaped oligonucleotides, each containing an isomer of thymine glycol or 5,6-dihydrothymine as a damaged base in the center, with a fluorophore and a quench...

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Detalhes bibliográficos
Main Authors: Matsumoto, Naoyuki, Toga, Tatsuya, Hayashi, Ryosuke, Sugasawa, Kaoru, Katayanagi, Katsuo, Ide, Hiroshi, Kuraoka, Isao, Iwai, Shigenori
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853145/
https://ncbi.nlm.nih.gov/pubmed/20110254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq022
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