A multistep damage recognition mechanism for global genomic nucleotide excision repair

A mammalian nucleotide excision repair (NER) factor, the XPC–HR23B complex, can specifically bind to certain DNA lesions and initiate the cell-free repair reaction. Here we describe a detailed analysis of its binding specificity using various DNA substrates, each containing a single defined lesion....

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Bibliografiska uppgifter
Huvudupphovsmän: Sugasawa, Kaoru, Okamoto, Tomoko, Shimizu, Yuichiro, Masutani, Chikahide, Iwai, Shigenori, Hanaoka, Fumio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2001
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC312644/
https://ncbi.nlm.nih.gov/pubmed/11238373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.866301
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