A multistep damage recognition mechanism for global genomic nucleotide excision repair

A mammalian nucleotide excision repair (NER) factor, the XPC–HR23B complex, can specifically bind to certain DNA lesions and initiate the cell-free repair reaction. Here we describe a detailed analysis of its binding specificity using various DNA substrates, each containing a single defined lesion....

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Dades bibliogràfiques

Publicat a:	Genes Dev
Autors principals:	Sugasawa, Kaoru, Okamoto, Tomoko, Shimizu, Yuichiro, Masutani, Chikahide, Iwai, Shigenori, Hanaoka, Fumio
Format:	Artigo
Idioma:	Inglês
Publicat:	Cold Spring Harbor Laboratory Press 2001
Matèries:	Research Paper
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312644/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.866301
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