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Acetaldehyde forms covalent GG intrastrand crosslinks in DNA
Carcinogens often generate mutable DNA lesions that contribute to cancer and aging. However, the chemical structure of tumorigenic DNA lesions formed by acetaldehyde remains unknown, although it has long been considered an environmental mutagen in alcohol, tobacco, and food. Here, we identify an ald...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6345987/ https://ncbi.nlm.nih.gov/pubmed/30679737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37239-6 |
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