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Acetaldehyde forms covalent GG intrastrand crosslinks in DNA

Carcinogens often generate mutable DNA lesions that contribute to cancer and aging. However, the chemical structure of tumorigenic DNA lesions formed by acetaldehyde remains unknown, although it has long been considered an environmental mutagen in alcohol, tobacco, and food. Here, we identify an ald...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Sonohara, Yuina, Yamamoto, Junpei, Tohashi, Kosuke, Takatsuka, Reine, Matsuda, Tomonari, Iwai, Shigenori, Kuraoka, Isao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345987/
https://ncbi.nlm.nih.gov/pubmed/30679737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37239-6
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