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Nucleocytoplasmic transport in C9orf72-mediated ALS/FTD

A GGGGCC hexanucleotide repeat expansion in C9orf72 is the most common genetic cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Recent studies indicate that disruption of nucleocytoplasmic transport pathways play a critical role in the pathogenesis of C9orf72-...

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Bibliografski detalji
Izdano u:Nucleus
Glavni autori: Zhang, Ke, Grima, Jonathan C., Rothstein, Jeffery D., Lloyd, Thomas E.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916865/
https://ncbi.nlm.nih.gov/pubmed/27116041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1172152
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