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Nucleocytoplasmic transport in C9orf72-mediated ALS/FTD
A GGGGCC hexanucleotide repeat expansion in C9orf72 is the most common genetic cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Recent studies indicate that disruption of nucleocytoplasmic transport pathways play a critical role in the pathogenesis of C9orf72-...
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| Publié dans: | Nucleus |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4916865/ https://ncbi.nlm.nih.gov/pubmed/27116041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1172152 |
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