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C9orf72-mediated ALS and FTD: multiple pathways to disease

The discovery that repeat expansions in the C9orf72 gene are a frequent cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) has revolutionized our understanding of these diseases. Substantial headway has been made in characterizing C9orf72-mediated disease and unravelling...

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Detalhes bibliográficos
Publicado no:Nat Rev Neurol
Main Authors: Balendra, Rubika, Isaacs, Adrian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417666/
https://ncbi.nlm.nih.gov/pubmed/30120348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41582-018-0047-2
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