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Specific biomarkers for C9orf72 FTD/ALS could expedite the journey towards effective therapies

A hexanucleotide repeat expansion in the C9orf72 gene is a common genetic cause of ALS and FTD. The repeats are translated into five different dipeptide repeat proteins (DPRs). In this issue, Lehmer et al (2017) demonstrate that one of these DPRs, poly(GP), can be measured in the CSF of individuals...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Balendra, Rubika, Moens, Thomas G, Isaacs, Adrian M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524429/
https://ncbi.nlm.nih.gov/pubmed/28533210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707848
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