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Specific biomarkers for C9orf72 FTD/ALS could expedite the journey towards effective therapies

A hexanucleotide repeat expansion in the C9orf72 gene is a common genetic cause of ALS and FTD. The repeats are translated into five different dipeptide repeat proteins (DPRs). In this issue, Lehmer et al (2017) demonstrate that one of these DPRs, poly(GP), can be measured in the CSF of individuals...

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Publicat a:EMBO Mol Med
Autors principals: Balendra, Rubika, Moens, Thomas G, Isaacs, Adrian M
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524429/
https://ncbi.nlm.nih.gov/pubmed/28533210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707848
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