Crystal Structures of the M(1) and M(4) Muscarinic Acetylcholine Receptors

Muscarinic M1–M5 acetylcholine receptors are G protein-coupled receptors (GPCRs) that regulate many vital functions of the central and peripheral nervous systems. In particular, the M1 and M4 receptor subtypes have emerged as attractive drug targets for treatments of neurological disorders, such as...

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Vydáno v:Nature
Hlavní autoři: Thal, David M., Sun, Bingfa, Feng, Dan, Nawaratne, Vindhya, Leach, Katie, Felder, Christian C., Bures, Mark G., Evans, David A., Weis, William I., Bachhawat, Priti, Kobilka, Tong Sun, Sexton, Patrick M., Kobilka, Brian K., Christopoulos, Arthur
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915387/
https://ncbi.nlm.nih.gov/pubmed/26958838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17188
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