Crystal Structures of the M(1) and M(4) Muscarinic Acetylcholine Receptors

Muscarinic M1–M5 acetylcholine receptors are G protein-coupled receptors (GPCRs) that regulate many vital functions of the central and peripheral nervous systems. In particular, the M1 and M4 receptor subtypes have emerged as attractive drug targets for treatments of neurological disorders, such as...

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Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Thal, David M., Sun, Bingfa, Feng, Dan, Nawaratne, Vindhya, Leach, Katie, Felder, Christian C., Bures, Mark G., Evans, David A., Weis, William I., Bachhawat, Priti, Kobilka, Tong Sun, Sexton, Patrick M., Kobilka, Brian K., Christopoulos, Arthur
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915387/
https://ncbi.nlm.nih.gov/pubmed/26958838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17188
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