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Crystal Structures of the M(1) and M(4) Muscarinic Acetylcholine Receptors

Muscarinic M1–M5 acetylcholine receptors are G protein-coupled receptors (GPCRs) that regulate many vital functions of the central and peripheral nervous systems. In particular, the M1 and M4 receptor subtypes have emerged as attractive drug targets for treatments of neurological disorders, such as...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Thal, David M., Sun, Bingfa, Feng, Dan, Nawaratne, Vindhya, Leach, Katie, Felder, Christian C., Bures, Mark G., Evans, David A., Weis, William I., Bachhawat, Priti, Kobilka, Tong Sun, Sexton, Patrick M., Kobilka, Brian K., Christopoulos, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915387/
https://ncbi.nlm.nih.gov/pubmed/26958838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17188
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