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Rapamycin: An InhibiTOR of Aging Emerges From the Soil of Easter Island
Rapamycin (sirolimus) is a macrolide immunosuppressant that inhibits the mechanistic target of rapamycin (mTOR) protein kinase and extends lifespan in model organisms including mice. Although rapamycin is an FDA-approved drug for select indications, a diverse set of negative side effects may preclud...
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| Yayımlandı: | J Gerontol A Biol Sci Med Sci |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906330/ https://ncbi.nlm.nih.gov/pubmed/27208895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glw090 |
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