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Rapamycin: An InhibiTOR of Aging Emerges From the Soil of Easter Island
Rapamycin (sirolimus) is a macrolide immunosuppressant that inhibits the mechanistic target of rapamycin (mTOR) protein kinase and extends lifespan in model organisms including mice. Although rapamycin is an FDA-approved drug for select indications, a diverse set of negative side effects may preclud...
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| Publicat a: | J Gerontol A Biol Sci Med Sci |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906330/ https://ncbi.nlm.nih.gov/pubmed/27208895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glw090 |
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