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Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J Mice

Inhibition of the mTOR (mechanistic target of rapamycin) signaling pathway by the FDA-approved drug rapamycin promotes life span in numerous model organisms and delays age-related disease in mice. However, the utilization of rapamycin as a therapy for age-related diseases will likely prove challengi...

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書目詳細資料
發表在:J Gerontol A Biol Sci Med Sci
Main Authors: Arriola Apelo, Sebastian I., Pumper, Cassidy P., Baar, Emma L., Cummings, Nicole E., Lamming, Dudley W.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906329/
https://ncbi.nlm.nih.gov/pubmed/27091134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glw064
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