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Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J Mice
Inhibition of the mTOR (mechanistic target of rapamycin) signaling pathway by the FDA-approved drug rapamycin promotes life span in numerous model organisms and delays age-related disease in mice. However, the utilization of rapamycin as a therapy for age-related diseases will likely prove challengi...
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| Publié dans: | J Gerontol A Biol Sci Med Sci |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906329/ https://ncbi.nlm.nih.gov/pubmed/27091134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glw064 |
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