Rapamycin Extends Life and Health in C57BL/6 Mice

Target of rapamycin inhibition by rapamycin feeding has previously been shown to extend life in genetically heterogeneous mice. To examine whether it similarly affected mouse health, we fed encapsulated rapamycin or a control diet to C57BL/6Nia mice of both sexes starting at 19 months of age. We per...

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Autori principali: Zhang, Yiqiang, Bokov, Alex, Gelfond, John, Soto, Vanessa, Ikeno, Yuji, Hubbard, Gene, Diaz, Vivian, Sloane, Lauren, Maslin, Keith, Treaster, Stephen, Réndon, Samantha, van Remmen, Holly, Ward, Walter, Javors, Martin, Richardson, Arlan, Austad, Steven N., Fischer, Kathleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038246/
https://ncbi.nlm.nih.gov/pubmed/23682161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glt056
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