Health Effects of Long-Term Rapamycin Treatment: The Impact on Mouse Health of Enteric Rapamycin Treatment from Four Months of Age throughout Life

Rapamycin, an mTOR inhibitor, has been shown to extend lifespan in a range of model organisms. It has been reported to extend lifespan in multiple strains of mice, administered chronically or acutely early or late in life. The ability of rapamycin to extend health (healthspan) as opposed to life is...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fischer, Kathleen E., Gelfond, Jonathan A. L., Soto, Vanessa Y., Han, Chul, Someya, Shinichi, Richardson, Arlan, Austad, Steven N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433347/
https://ncbi.nlm.nih.gov/pubmed/25978367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126644
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