Health Effects of Long-Term Rapamycin Treatment: The Impact on Mouse Health of Enteric Rapamycin Treatment from Four Months of Age throughout Life

Rapamycin, an mTOR inhibitor, has been shown to extend lifespan in a range of model organisms. It has been reported to extend lifespan in multiple strains of mice, administered chronically or acutely early or late in life. The ability of rapamycin to extend health (healthspan) as opposed to life is...

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Publicat a:PLoS One
Autors principals: Fischer, Kathleen E., Gelfond, Jonathan A. L., Soto, Vanessa Y., Han, Chul, Someya, Shinichi, Richardson, Arlan, Austad, Steven N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433347/
https://ncbi.nlm.nih.gov/pubmed/25978367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126644
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