Chronic inhibition of mTOR by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

Aging is, by far, the greatest risk factor for most neurodegenerative diseases. In non-diseased conditions, normal aging can also be associated with declines in cognitive function that significantly affect quality of life in the elderly. It was recently shown that inhibition of mTOR activity in mice...

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Detalhes bibliográficos
Main Authors: Halloran, Jonathan, Hussong, Stacy, Burbank, Raquel, Podlutskaya, Natalia, Fischer, Keyt, Sloane, Lauren, Austad, Steven N., Strong, Randy, Richardson, Arlan, Hart, Matthew, Galvan, Veronica
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454865/
https://ncbi.nlm.nih.gov/pubmed/22750207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.06.054
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