Chronic inhibition of mTOR by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

Aging is, by far, the greatest risk factor for most neurodegenerative diseases. In non-diseased conditions, normal aging can also be associated with declines in cognitive function that significantly affect quality of life in the elderly. It was recently shown that inhibition of mTOR activity in mice...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Halloran, Jonathan, Hussong, Stacy, Burbank, Raquel, Podlutskaya, Natalia, Fischer, Keyt, Sloane, Lauren, Austad, Steven N., Strong, Randy, Richardson, Arlan, Hart, Matthew, Galvan, Veronica
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454865/
https://ncbi.nlm.nih.gov/pubmed/22750207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.06.054
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