Chronic inhibition of mTOR by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

Aging is, by far, the greatest risk factor for most neurodegenerative diseases. In non-diseased conditions, normal aging can also be associated with declines in cognitive function that significantly affect quality of life in the elderly. It was recently shown that inhibition of mTOR activity in mice...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Halloran, Jonathan, Hussong, Stacy, Burbank, Raquel, Podlutskaya, Natalia, Fischer, Keyt, Sloane, Lauren, Austad, Steven N., Strong, Randy, Richardson, Arlan, Hart, Matthew, Galvan, Veronica
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454865/
https://ncbi.nlm.nih.gov/pubmed/22750207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.06.054
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