Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau: EFFECTS ON COGNITIVE IMPAIRMENTS

Accumulation of amyloid-β (Aβ) and Tau is an invariant feature of Alzheimer disease (AD). The upstream role of Aβ accumulation in the disease pathogenesis is widely accepted, and there is strong evidence showing that Aβ accumulation causes cognitive impairments. However, the molecular mechanisms lin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Caccamo, Antonella, Majumder, Smita, Richardson, Arlan, Strong, Randy, Oddo, Salvatore
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Molecular Bases of Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857107/
https://ncbi.nlm.nih.gov/pubmed/20178983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.100420
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg