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Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits

Previous studies have shown that inducing autophagy ameliorates early cognitive deficits associated with the build-up of soluble amyloid-β (Aβ). However, the effects of inducing autophagy on plaques and tangles are yet to be determined. While soluble Aβ and tau represent toxic species in Alzheimer&#...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Majumder, Smita, Richardson, Arlan, Strong, Randy, Oddo, Salvatore
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182203/
https://ncbi.nlm.nih.gov/pubmed/21980451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025416
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