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Sex‐ and tissue‐specific changes in mTOR signaling with age in C57BL/6J mice

Inhibition of the mTOR (mechanistic Target Of Rapamycin) signaling pathway robustly extends the lifespan of model organisms including mice. The precise molecular mechanisms and physiological effects that underlie the beneficial effects of rapamycin are an exciting area of research. Surprisingly, whi...

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Publicat a:Aging Cell
Autors principals: Baar, Emma L., Carbajal, Kathryn A., Ong, Irene M., Lamming, Dudley W.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717274/
https://ncbi.nlm.nih.gov/pubmed/26695882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12425
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