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Sex‐ and tissue‐specific changes in mTOR signaling with age in C57BL/6J mice
Inhibition of the mTOR (mechanistic Target Of Rapamycin) signaling pathway robustly extends the lifespan of model organisms including mice. The precise molecular mechanisms and physiological effects that underlie the beneficial effects of rapamycin are an exciting area of research. Surprisingly, whi...
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| Pubblicato in: | Aging Cell |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4717274/ https://ncbi.nlm.nih.gov/pubmed/26695882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12425 |
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