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Diminished mTOR signaling: a common mode of action for endocrine longevity factors

Since the initial observation that a calorie-restricted (CR) diet can extend rodent lifespan, many genetic and pharmaceutical interventions that also extend lifespan in mammals have been discovered. The mechanism by which CR and these other interventions extend lifespan is the subject of significant...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Springerplus
Glavni avtor: Lamming, Dudley W
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320218/
https://ncbi.nlm.nih.gov/pubmed/25674466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-735
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