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Translational Geroscience: Targeting mTOR Signaling to Promote Healthy Longevity

The FDA approved drug rapamycin delays aging and increases lifespan in yeast, nematodes, fruit flies, and mice. Nevertheless, important questions exist regarding the translational potential of rapamycin and other mTOR inhibitors for human aging, and the optimal dose, duration, and mechanisms of acti...

詳細記述

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書誌詳細
出版年:Innov Aging
第一著者: Kaeberlein, M.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248758/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.2680
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