Development of GABA(A) Receptor Subtype-Selective Imidazobenzodiazepines as Novel Asthma Treatments

Recent studies have demonstrated that subtype-selective GABA(A) receptor modulators are able to relax pre-contracted human airway smooth muscle ex vivo and reduce airway hyper-responsiveness in mice upon aerosol administration. Our goal in this study was to investigate systemic administration of sub...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Pharm
Hauptverfasser: Forkuo, Gloria S., Guthrie, Margaret L., Yuan, Nina Y., Nieman, Amanda N., Kodali, Revathi, Jahan, Rajwana, Stephen, Michael R., Yocum, Gene T., Treven, Marco, Poe, Michael M., Li, Guanguan, Yu, Olivia B., Hartzler, Benjamin D., Zahn, Nicolas M., Ernst, Margot, Emala, Charles W., Stafford, Douglas C., Cook, James M., Arnold, Leggy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899155/
https://ncbi.nlm.nih.gov/pubmed/27120014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00159
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge