Reduced allergic lung inflammation and airway responsiveness in mice lacking the cytoskeletal protein gelsolin

por Mikami, Maya, Yocum, Gene T., Heller, Nicola M., Emala, Charles W.
Publicado no Am J Physiol Lung Cell Mol Physiol (2020)

Ginger and its bioactive component 6-shogaol mitigate lung inflammation in a murine asthma model

por Yocum, Gene T., Hwang, Julie J., Mikami, Maya, Danielsson, Jennifer, Kuforiji, Aisha S., Emala, Charles W.
Publicado no Am J Physiol Lung Cell Mol Physiol (2020)

Agonism of the TMEM16A calcium-activated chloride channel modulates airway smooth muscle tone

por Danielsson, Jennifer, Kuforiji, Aisha S., Yocum, Gene T., Zhang, Yi, Xu, Dingbang, Gallos, George, Emala, Charles W.
Publicado no Am J Physiol Lung Cell Mol Physiol (2020)

MMP-9 levels in elderly patients with cognitive dysfunction after carotid surgery

por Gaudet, John G., Yocum, Gene T., Lee, Susie S., Granat, Anna, Mikami, Maya, Connolly, E. Sander, Heyer, Eric J.
Publicado em 2010

Neurocognitive Performance in Hypertensive Patients after Spine Surgery

por Yocum, Gene T., Gaudet, John G., Teverbaugh, Lauren A., Quest, Donald O., McCormick, Paul C., Connolly, E. Sander, Heyer, Eric J.
Publicado em 2009

Targeting the γ-Aminobutyric Acid A Receptor α4 Subunit in Airway Smooth Muscle to Alleviate Bronchoconstriction

por Yocum, Gene T., Gallos, George, Zhang, Yi, Jahan, Rajwana, Stephen, Michael Rajesh, Varagic, Zdravko, Puthenkalam, Roshan, Ernst, Margot, Cook, James M., Emala, Charles W.
Publicado no Am J Respir Cell Mol Biol (2016)

Role of transient receptor potential vanilloid 1 in the modulation of airway smooth muscle tone and calcium handling

por Yocum, Gene T., Chen, Jun, Choi, Christine H., Townsend, Elizabeth A., Zhang, Yi, Xu, Dingbang, Fu, Xiao W., Sanderson, Michael J., Emala, Charles W.
Publicado no Am J Physiol Lung Cell Mol Physiol (2017)

GABA(A) receptor α(4)-subunit knockout enhances lung inflammation and airway reactivity in a murine asthma model

por Yocum, Gene T., Turner, Damian L., Danielsson, Jennifer, Barajas, Matthew B., Zhang, Yi, Xu, Dingbang, Harrison, Neil L., Homanics, Gregg E., Farber, Donna L., Emala, Charles W.
Publicado no Am J Physiol Lung Cell Mol Physiol (2017)

Selective targeting of the α5-subunit of GABA(A) receptors relaxes airway smooth muscle and inhibits cellular calcium handling

por Gallos, George, Yocum, Gene T., Siviski, Matthew E., Yim, Peter D., Fu, Xiao Wen, Poe, Michael M., Cook, James M., Harrison, Neil, Perez-Zoghbi, Jose, Emala, Charles W.
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)

Nebulized MIDD0301 Reduces Airway Hyperresponsiveness in Moderate and Severe Murine Asthma Models

por Zahn, Nicolas M., Mikulsky, Brandon N., Roni, M. S. Rashid, Yocum, Gene T., Mian, Md Yeunus, Knutson, Daniel E., Cook, James M., Emala, Charles W., Stafford, Douglas C., Arnold, Leggy A.
Publicado no ACS Pharmacol Transl Sci (2020)

A novel GABA(A) receptor ligand MIDD0301 with limited blood-brain barrier penetration relaxes airway smooth muscle ex vivo and in vivo

por Yocum, Gene T., Perez-Zoghbi, Jose F., Danielsson, Jennifer, Kuforiji, Aisha S., Zhang, Yi, Li, Guanguan, Rashid Roni, M. S., Kodali, Revathi, Stafford, Douglas C., Arnold, Leggy A., Cook, James M., Emala, Charles W.
Publicado no Am J Physiol Lung Cell Mol Physiol (2019)

Inducible Nitric Oxide Synthase Promoter Polymorphism Affords Protection Against Cognitive Dysfunction After Carotid Endarterectomy

por Yocum, Gene T., Gaudet, John G., Lee, Susie S., Stern, Yaakov, Teverbaugh, Lauren A., Sciacca, Robert R., Emala, Charles W., Quest, Donald O., McCormick, Paul C., McKinsey, James F., Morrissey, Nicholas J., Solomon, Robert A., Connolly, E. Sander, Heyer, Eric J.
Publicado em 2009

Optimization of Substituted Imidazobenzodiazepines as Novel Asthma Treatments

por Jahan, Rajwana, Stephen, Michael Rajesh, Forkuo, Gloria S., Kodali, Revathi, Guthrie, Margaret L., Nieman, Amanda N., Yuan, Nina Y., Zahn, Nicolas M., Poe, Michael M., Li, Guanguan, Yu, Olivia B., Yocum, Gene T., Emala, Charles W., Stafford, Douglas C., Cook, James M., Arnold, Leggy A.
Publicado no Eur J Med Chem (2016)

A novel orally available asthma drug candidate that reduces smooth muscle constriction and inflammation by targeting GABA(A) receptors in the lung

por Forkuo, Gloria S., Nieman, Amanda N., Kodali, Revathi, Zahn, Nicolas M., Li, Guanguan, Rashid Roni, M. S., Stephen, Michael Rajesh, Harris, Ted W., Jahan, Rajwana, Guthrie, Margaret L., Yu, Olivia B., Fisher, Janet L., Yocum, Gene T., Emala, Charles W., Steeber, Douglas A., Stafford, Douglas C., Cook, James M., Arnold, Leggy A.
Publicado no Mol Pharm (2018)

Development of GABA(A) Receptor Subtype-Selective Imidazobenzodiazepines as Novel Asthma Treatments

por Forkuo, Gloria S., Guthrie, Margaret L., Yuan, Nina Y., Nieman, Amanda N., Kodali, Revathi, Jahan, Rajwana, Stephen, Michael R., Yocum, Gene T., Treven, Marco, Poe, Michael M., Li, Guanguan, Yu, Olivia B., Hartzler, Benjamin D., Zahn, Nicolas M., Ernst, Margot, Emala, Charles W., Stafford, Douglas C., Cook, James M., Arnold, Leggy A.
Publicado no Mol Pharm (2016)

Alleviation of Multiple Asthmatic Pathologic Features with Orally Available and Subtype Selective GABA(A) Receptor Modulators

por Forkuo, Gloria S., Nieman, Amanda N., Yuan, Nina Y., Kodali, Revathi, Yu, Olivia B., Zahn, Nicolas M., Jahan, Rajwana, Li, Guanguan, Stephen, Michael Rajesh, Guthrie, Margaret L., Poe, Michael M., Hartzler, Benjamin D., Harris, Ted W., Yocum, Gene T., Emala, Charles W., Steeber, Douglas A., Stafford, Douglas C., Cook, James M., Arnold, Leggy A.
Publicado no Mol Pharm (2017)