Pharmacological and antihyperalgesic properties of the novel α2/3 preferring GABA(A) receptor ligand MP-III-024

γ-aminobutyric acid type A (GABA(A)) receptors are located in spinal nociceptive circuits where they mediate the transmission of pain sensory signals from the periphery to higher centers. Benzodiazepine-type drugs bind GABA(A), receptors containing α1, α2, α3, and α5 subunits (α1GABA(A), α2GABA(A),...

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Publicado no:Brain Res Bull
Main Authors: Fischer, Bradford D., Schlitt, Raymond J., Hamade, Bryan Z, Rehman, Sabah, Ernst, Margot, Poe, Michael M., Li, Guanguan, Kodali, Revathi, Arnold, Leggy A., Cook, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501353/
https://ncbi.nlm.nih.gov/pubmed/28267561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2017.03.001
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