Functional modulation of G-protein coupled receptors during Parkinson disease-like neurodegeneration

G-protein coupled dopamine and metabotropic glutamate receptors (mGlu) can modulate neurotransmission during Parkinson's disease (PD)-like neurodegeneration. PET imaging studies in a unilateral dopamine denervation model (6-OHDA) showed a significant inverse correlation of presynaptic mGlu(4) a...

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Publicat a:Neuropharmacology
Autors principals: Jenkins, Bruce, Zhu, Aijun, Poutiainen, Pekka, Choi, Ji-Kyung, Kil, Kun-Eek, Zhang, Zhaoda, Kuruppu, Darshini, Aytan, Nurgul, Dedeoglu, Alpaslan, Brownell, Anna-Liisa
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896842/
https://ncbi.nlm.nih.gov/pubmed/26581500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.11.010
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