Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

Thiamin is essential for normal metabolism in pancreatic acinar cells (PAC) and is obtained from their microenvironment through specific plasma-membrane transporters, converted to thiamin pyrophosphate (TPP) in the cytoplasm, followed by uptake of TPP by mitochondria through the mitochondrial TPP (M...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Am J Physiol Gastrointest Liver Physiol
Huvudupphovsmän: Srinivasan, Padmanabhan, Thrower, Edwin C., Gorelick, Fred S., Said, Hamid M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2016
Ämnen:
Pancreatic Physiology/Pathophysiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888549/
https://ncbi.nlm.nih.gov/pubmed/26999808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00461.2015
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk