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Chronic alcohol exposure affects pancreatic acinar mitochondrial thiamin pyrophosphate uptake: studies with mouse 266-6 cell line and primary cells

Thiamin is essential for normal metabolic activity of all mammalian cells, including those of the pancreas. Cells obtain thiamin from their surroundings and enzymatically convert it into thiamin pyrophosphate (TPP) in the cytoplasm; TPP is then taken up by mitochondria via a specific carrier the mit...

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Dades bibliogràfiques
Publicat a:Am J Physiol Gastrointest Liver Physiol
Autors principals: Srinivasan, Padmanabhan, Nabokina, Svetlana, Said, Hamid M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628969/
https://ncbi.nlm.nih.gov/pubmed/26316591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00226.2015
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