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Chronic alcohol exposure affects pancreatic acinar mitochondrial thiamin pyrophosphate uptake: studies with mouse 266-6 cell line and primary cells

Thiamin is essential for normal metabolic activity of all mammalian cells, including those of the pancreas. Cells obtain thiamin from their surroundings and enzymatically convert it into thiamin pyrophosphate (TPP) in the cytoplasm; TPP is then taken up by mitochondria via a specific carrier the mit...

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Опубликовано в: :Am J Physiol Gastrointest Liver Physiol
Главные авторы: Srinivasan, Padmanabhan, Nabokina, Svetlana, Said, Hamid M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628969/
https://ncbi.nlm.nih.gov/pubmed/26316591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00226.2015
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