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Mechanisms involved in the inhibitory effect of chronic alcohol exposure on pancreatic acinar thiamin uptake

Pancreatic acinar cells (PAC) obtain thiamin from the circulation via a carrier-mediated process that involves thiamin transporters 1 and 2 (THTR-1 and THTR-2; products of SLC19A2 and SLC19A3, respectively). Chronic alcohol exposure of PAC inhibits thiamin uptake, and, on the basis of in vitro studi...

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Detalhes bibliográficos
Main Authors: Srinivasan, Padmanabhan, Subramanian, Veedamali S., Said, Hamid M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962591/
https://ncbi.nlm.nih.gov/pubmed/24525018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00420.2013
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