Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells

Thiamin (vitamin B1), a member of the water-soluble family of vitamins, is essential for normal cellular functions; its deficiency results in oxidative stress and mitochondrial dysfunction. Pancreatic acinar cells (PAC) obtain thiamin from the circulation using a specific carrier-mediated process me...

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Pubblicato in:PLoS One
Autori principali: Srinivasan, Padmanabhan, Thrower, Edwin C., Loganathan, Gopalakrishnan, Balamurugan, A. N., Subramanian, Veedamali S., Gorelick, Fred S., Said, Hamid M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669105/
https://ncbi.nlm.nih.gov/pubmed/26633299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143575
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