Molecular and cellular mechanisms of pancreatic injury

Por Thrower, Edwin C., Gorelick, Fred S., Husain, Sohail Z.
Publicado em 2010

Risk factors for pancreatic cancer: underlying mechanisms and potential targets

Por Kolodecik, Thomas, Shugrue, Christine, Ashat, Munish, Thrower, Edwin C.
Publicado em 2014

The Emerging Role of Smoking in the Development of Pancreatitis

Por Alexandre, Martine, Pandol, Stephen J., Gorelick, Fred S., Thrower, Edwin C.
Publicado em 2011

Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

Por Srinivasan, Padmanabhan, Thrower, Edwin C., Gorelick, Fred S., Said, Hamid M.
Publicado no Am J Physiol Gastrointest Liver Physiol (2016)

Vacuolar ATPase Regulates Zymogen Activation in Pancreatic Acini

Por Waterford, Stephen D., Kolodecik, Thomas R., Thrower, Edwin C., Gorelick, Fred S.
Publicado em 2004

Zymogen activation in a reconstituted pancreatic acinar cell system

Por Thrower, Edwin C., Diaz de Villalvilla, Alexander P. E., Kolodecik, Thomas R., Gorelick, Fred S.
Publicado em 2005

Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 Å resolution

Por Jiang, Qiu-Xing, Thrower, Edwin C., Chester, David W., Ehrlich, Barbara E., Sigworth, Fred J.
Publicado em 2002

Activation of Soluble Adenylyl Cyclase Protects against Secretagogue Stimulated Zymogen Activation in Rat Pancreaic Acinar Cells

Por Kolodecik, Thomas R., Shugrue, Christine A., Thrower, Edwin C., Levin, Lonny R., Buck, Jochen, Gorelick, Fred S.
Publicado em 2012

Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells

Por Srinivasan, Padmanabhan, Thrower, Edwin C., Loganathan, Gopalakrishnan, Balamurugan, A. N., Subramanian, Veedamali S., Gorelick, Fred S., Said, Hamid M.
Publicado no PLoS One (2015)

Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats

Por Bhoomagoud, Madhavi, Jung, Thomas, Atladottir, Jorunn, Kolodecik, Thomas R, Shugrue, Christine, Chaudhuri, Anamika, Thrower, Edwin C, Gorelick, Fred S
Publicado em 2009

Tissue Pharmacology of Da-Cheng-Qi Decoction in Experimental Acute Pancreatitis in Rats

Por Zhao, Xianlin, Zhang, Yumei, Li, Juan, Wan, Meihua, Zhu, Shifeng, Guo, Hui, Xiang, Jin, Thrower, Edwin C., Tang, Wenfu
Publicado no Evid Based Complement Alternat Med (2015)

Cerulein hyperstimulation decreases AMP-activated protein kinase levels at the site of maximal zymogen activation

Por Shugrue, Christine A., Alexandre, Martine, de Villalvilla, Alexander Diaz, Kolodecik, Thomas R., Young, Lawrence H., Gorelick, Fred S., Thrower, Edwin C.
Publicado em 2012

A novel protein kinase D inhibitor attenuates early events of experimental pancreatitis in isolated rat acini

Por Thrower, Edwin C., Yuan, Jingzhen, Usmani, Ashar, Liu, Yannan, Jones, Courtney, Minervini, Samantha N., Alexandre, Martine, Pandol, Stephen J., Guha, Sushovan
Publicado em 2011

The novel protein kinase C isoforms -δ and -ε modulate caerulein-induced zymogen activation in pancreatic acinar cells

Por Thrower, Edwin C., Osgood, Sara, Shugrue, Christine A., Kolodecik, Thomas R., Chaudhuri, Anamika M., Reeve, Joseph R., Pandol, Stephen J., Gorelick, Fred S.
Publicado em 2008