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Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats
BACKGROUND AND AIMS: Protease activation within the pancreatic acinar cell is a key early event in acute pancreatitis and may require low pH intracellular compartments. Clinical studies suggest that acidosis may affect the risk for developing pancreatitis. We hypothesized that exposure to an acid lo...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736307/ https://ncbi.nlm.nih.gov/pubmed/19454288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.05.041 |
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