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Low Extracellular pH Induces Damage in the Pancreatic Acinar Cell by Enhancing Calcium Signaling

Low extracellular pH (pHe) occurs in a number of clinical conditions and sensitizes to the development of pancreatitis. The mechanisms responsible for this sensitization are unknown. Because abnormal Ca(2+) signaling underlies many of the early steps in the pathogenesis of pancreatitis, we evaluated...

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Bibliografiska uppgifter
Huvudupphovsmän: Reed, Anamika M., Husain, Sohail Z., Thrower, Edwin, Alexandre, Martine, Shah, Ahsan, Gorelick, Fred S., Nathanson, Michael H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023488/
https://ncbi.nlm.nih.gov/pubmed/21084290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.158329
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