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Low Extracellular pH Induces Damage in the Pancreatic Acinar Cell by Enhancing Calcium Signaling
Low extracellular pH (pHe) occurs in a number of clinical conditions and sensitizes to the development of pancreatitis. The mechanisms responsible for this sensitization are unknown. Because abnormal Ca(2+) signaling underlies many of the early steps in the pathogenesis of pancreatitis, we evaluated...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023488/ https://ncbi.nlm.nih.gov/pubmed/21084290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.158329 |
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