Cigarette toxin 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces experimental pancreatitis through α7 nicotinic acetylcholine receptors (nAChRs) in mice

Clinical studies have shown that cigarette smoking is a dose-dependent and independent risk factor for acute pancreatitis. Cigarette smoke contains nicotine which can be converted to the potent receptor ligand and toxin, NNK [4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone]. Previously, we have shown...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Alahmari, A. A., Sreekumar, B., Patel, V., Ashat, M., Alexandre, M., Uduman, A. K., Akinbiyi, E. O., Ceplenski, A., Shugrue, C. A., Kolodecik, T. R., Tashkandi, N., Messenger, S. W., Groblewski, G. E., Gorelick, F. S., Thrower, E. C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988302/
https://ncbi.nlm.nih.gov/pubmed/29870540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197362
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items