Robust transcriptome-wide discovery of RNA binding protein binding sites with enhanced CLIP (eCLIP)

As RNA binding proteins (RBPs) play essential roles in cellular physiology by interacting with target RNAs, binding site identification by UV-crosslinking and immunoprecipitation (CLIP) of ribonucleoprotein complexes is critical to understanding RBP function. However, current CLIP protocols are tech...

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Publicado en:Nat Methods
Autores principales: Van Nostrand, Eric L., Pratt, Gabriel A., Shishkin, Alexander A., Gelboin-Burkhart, Chelsea, Fang, Mark Y., Sundararaman, Balaji, Blue, Steven M., Nguyen, Thai B., Surka, Christine, Elkins, Keri, Stanton, Rebecca, Rigo, Frank, Guttman, Mitchell, Yeo, Gene W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887338/
https://ncbi.nlm.nih.gov/pubmed/27018577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3810
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